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Home > Products > Pharmaceutical And Medical > Central Nervous System Drugs > 98% (HPLC) Tianeptine Sodium Salt Hydrate for Antidepressant Drugs 30123-17-2

98% (HPLC) Tianeptine Sodium Salt Hydrate for Antidepressant Drugs 30123-17-2

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Basic Info

Model No.:  Antidepressant Drugs

Product Description

Model NO.: Antidepressant Drugs Customized: Customized Suitable for: Adult Purity: >99% Payment Terms: Western Union, Moneygram, Jp Morgan Chase Name: Dabigatran Etexilate Intermediates Transport Package: Disguised Origin: China Powder: No Certification: GMP, ISO 9001, USP, BP State: Powder CAS: 30123-17-2 Grade: Pharmaceutical Grade Trademark: SENDI Specification: White powder 98% (HPLC) Tianeptine Sodium Salt Hydrate For Antidepressant Drugs 30123-17-2

Product Name:Tianeptine sodium salt
CAS: 30123-17-2;
Synonyms: TIANEPTINE SODIUM; TIANEPTINE SODIUM SALT; sodium 7-((3-chloro-6,11-dihydro-6-methyldibenzo(c,f)(1,2)thiazepin-11-yl)amino)heptanoate s,s-dioxide; 7-[(3-Chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic Acid S,S-Dioxide Sodium Salt; S-1574;Stablon;7-[(3-chloro-6,11-dihydro-6-methyl-dibenzo[c,f][1,2]thiazepine-11-yl)amino]heptanoic acid s,s dioxide sodium salt; Sodium 7-((3-chloro-6,11-dihydro-6-methyldibenzo(c,f)(1,2)thiazepin-11-yl)amino)heptanoate S,S-dioxide;
 MF: C21H24ClN2NaO4S ;
MW: 458.93;
EINECS: 250-059-3;

Usage:Tianeptine (INN) (Stablon, Coaxil, Tatinol) is a selective serotonin reuptake enhancer (SSRE) drug used for treating major depressive episodes (mild, moderate, or severe) it is used as stabilizer.

Tianeptine Sodium salt is one of the rising ingredients recently for dietary supplements especially in the US but it is already been used as medicine in the market in France and other European countries for a long time.

Tianeptine sodium salt is a salt of Tianeptine. Tianeptine, a tricyclic compound, is a selective facilitator of 5HT (serotonin; sc201146) uptake in vitro and in vivo. Additionally, Tianeptine is reported to act as a selective inhibitor of dopamine uptake and is similar to amineptine. Tianeptine does not have a noted effect on monoamine uptake. In a study utilizing purified synaptosomes from rat brain, Tianeptine was reported to enhance serotonin uptake in selective brain regions. Purified synaptosomes were obtained from rats and incubated with tritiumHT and Tianeptine in vitro . The synaptosomes were then analyzed for uptake and release of 5-HT via a liquid scintillation counter.

Tianeptine Sodium Salt comes in different brands namely Stablon, Coaxil, Tatinol, Tianeurax and Salymbraand is now discovered to be a potential nootropic agent for it has anxiolytic properties (anti-depressant drug) but it performs unique activities compared to other antidepressant drugs and have somecognitive boosting effects like better memory, advanced learning and better thoughts or comprehension.

COA

Assay (on anhydrous basis)

99%-101.0%

99.50%

Solubility

Freely soluble in water and methanol

Complies

Identification

Reaction positive

Complies

Related substance

Individual impurity: ≤0.1%

0.080%

 

Total impurities: ≤0.4%

0.230%

Methanol

≤ 0.3%

Not detected

 

≤ 0.06%

Not detected

 

≤ 0.5%

0.45%

Water

≤5.0%

0.55%

Appearance

White to yellowish powder,hygroscopic

off-white powder,hygroscopic

Dosage

The dosage taken especially as antidepressant ranges from 25 to 50 mg/day but specifically 37.5mg/day is found out to be more effective which was based on the different experiments conducted.

Application
Sodium has been assayed as a steatosis-positive inducer in HepG2 cells[4]. Tianeptine has also been used to study effects on rats exposed to swim endurance tests (SETs). This study reported that tianeptine increased swimming time in rats undergoing SET. Moreover, tianeptine also increased total cholesterol and LDL, while triglyceride levels were decreased. Thus, tianeptine may be involved in the pathogenesis of metabolic syndrome

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