Powder: Yes Certification: GMP, ISO 9001, Ep5 State: Solid Model No: 1722-62-9 Standard: USP/Bp MOQ: 10g Trademark: Sendi Specification: 1kg/bag, 25KG HS Code: 3001200010 Customized: Non-Customized Suitable for: Adult Purity: >99% Characters: White Crystalline Powder Sample: Free Transportation: DHL, UPS, TNT, EMS, FedEx or Other Transport Package: 1kg/Bag, 25kg Origin: China Mepivacaine hydrochloride hcl Local Anesthetic Drugs
Mepivacaina Carbocaine CAS 1722-62-9
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|Product name ||Mepivacaine hydrochloride |
|Other name ||Mepivacaine hcl |
|CAS No. ||1722-62-9 |
|Molecular formula ||C15H22N2O.ClH |
|Molecular weight ||282.81 |
|EINECS ||217-023-9 |
|Appearance ||White or off white crystalline powder |
|Standard adopted ||USP |
|Melting Pcint ||255-257C (dec.) |
|Assay ||99.25% |
|Usage ||local anaesthetic |
|Storage ||Closed, confined and shading preservation |
What is Mepivacaine hydrochloride ?
Mepivicaine hydrochloride is a local anesthetic of the amide type. Mepivicaine as a reasonably rapid onset and medium duration and is known by the proprietary names as Carbocaine and Polocaine. Mepivicaine is used in local infiltration and regional anesthesia. Systemic absorption of local anesthetics produces effects on the cardiovascular and central nervous systems. At blood concentrations achieved with normal therapeutic doses, changes in cardiac conduction, excitability, refractoriness, contractility, and peripheral vascular resistance are minimal.
Half life of Mepivacaine hydrochloride
The half-life of mepivacaine in adults is 1.9 to 3.2 hours and in neonates 8.7 to
Mepivacaine hydrochloride of action
Local anesthetics block the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. In general, the progression of anesthesia is related to the diameter, myelination, and conduction velocity of affected nerve fibers. Clinically, the order of loss of nerve function is as follows: pain, temperature, touch, proprioception, and skeletal muscle tone.
Mepivacaine hydrochloride of Absorption
Absorbed locally. The rate of systemic absorption of local anesthetics is dependent upon the total dose and concentration of drug administered, the route of administration, the vascularity of the administration site, and the presence or absence of epinephrine in the anesthetic solution.
Rapidly metabolized, with only a small percentage of the anesthetic (5 percent to 10 percent) being excreted unchanged in the urine. The liver is the principal site of metabolism, with over 50% of the administered dose being excreted into the bile as metabolites.
Route of elimination.It is rapidly metabolized, with only a small percentage of the anesthetic (5 percent to 10 percent) being excreted unchanged in the urine.The liver is the principal site of metabolism, with over 50% of the administered dose being excreted into the bile as metabolites.
Other local Anesthetic drugs
|NO.1 ||Tetracaine ||CAS:94-24-6 |
|NO.2 ||Tetracaine hydrochloride ||CAS:136-47-0 |
|NO.3 ||Benzocaine ||CAS:94-09-7 |
|NO.4 ||Benzocaine hydrochloride ||CAS:23239-88-5 |
|NO.5 ||Bupivacaine ||CAS:2180-92-9 |
|NO.6 ||Bupivacaine Hydrochloride ||CAS:14252-80-3 |
|NO.7 ||Dibucaine hydrochloride ||CAS:61-12-1 |
|NO.8 ||Pramoxine hydrochloride ||CAS:637-58-1 |
|NO.9 ||Procaine ||CAS:59-46-1 |
|NO.10 ||Procaine Hydrochloride ||CAS:51-05-8 |
|NO.11 ||Articaine ||CAS:23964-58-1 |
|NO.12 ||Articaine hydrochloride ||CAS:23964-57-0 |
|NO.13 ||Levobupivacaine ||CAS:27262-47-1 |
|NO.14 ||Levobupivacaine hydrochloride ||CAS:27262-48-2 |
|NO.15 ||Lidocaine ||CAS:137-58-6 |
|NO.16 ||Lidocaine hydrochloride ||CAS:73-78-9 |
|NO.17 ||Proparacaine hydrochloride ||CAS:5875-06-9 |
|NO.18 ||Prilocaine ||CAS:721-50-6 |
|NO.19 ||Prilocaine hydrochloride ||CAS:1786-81-8 |
|NO.20 ||Ropivacaine ||CAS:84057-95-4 |
|NO.21 ||Ropivacaine hydrochloride ||CAS:98717-15-8 |
|NO.22 ||Procainamide hydrochloride ||CAS:614-39-1 |
| || || |
|NO.24 ||Ropivacaine mesylate ||CAS:854056-07-8 |
|NO.25 ||Dyclonine hydrochloride ||CAS:536-43-6 |
|NO.26 ||Mepivacaine hydrochloride ||CAS:1722-62-9 |
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Product Categories : Local Anesthetic Drugs