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Home > Products > Pharmaceutical And Medical > Others Pharmaceutical And Medical > Female Synthetic Hormone Nafarelin Acetate (synarel) 76932-56-4 for Treating Endometriosis

Female Synthetic Hormone Nafarelin Acetate (synarel) 76932-56-4 for Treating Endometriosis

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Basic Info

Model No.:  76932-56-4

Product Description

Model NO.: 76932-56-4 Customized: Customized Suitable for: Adult Purity: >99% Payment Terms: Western Union, Moneygram, Jp Morgan Chase Shelf Life: 2 Years for Nafarelin Acetate Product Categories: Peptide Transport Package: Disguised Origin: China Powder: No Certification: GMP, ISO 9001, USP, BP State: Powder CAS Number: 76932-56-4 Category: Pharmaceutical Raw Materials Usage: Nafarelin Acetate Is Used in Female Infertility an Trademark: SENDI Specification: White Crystalline powder Female Synthetic Hormone Nafarelin Acetate (synarel) 76932-56-4 for Treating Endometriosis

Nafarelin Acetate

What are the precautions when taking nafarelin acetate for central precocious puberty (Synarel)?

Before using nafarelin, tell your doctor or pharmacist if you are allergic to it; or to GnRH or other GnRH-like hormones (e.g., leuprolide); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

This medication should not be used if you have certain medical conditions. Before using this medicine, consult your doctor or pharmacist if you have: unexplained abnormal vaginal bleeding.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: smoking, daily alcohol use, bone loss (osteoporosis) or family history of osteoporosis, polycystic ovarian disease, high cholesterol/triglyceride levels.
 
Product name
Nafarelin Acetate

CAS NO.

76932-56-4

Synonyms

Nafarelin Acetate

Category
Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Purity
99% Nafarelin Acetate

Appearance

Nafarelin Acetate powder

Shelf life
2 years for Nafarelin Acetate
Usage
Nafarelin Acetate is used in female infertility and endometriosis.

Storage
Nafarelin Acetate should be stored in a well-closed containerat low temperature, keep away from moisture, heat and light.

COA
 
Item Specification Result
Appearance White powder Complies
Identification Positive Complies
Assay 98.0% min 98.2%
Loss on Drying 6.0%max. 5.8%
Acetate Content(by HPLC) 10.0%max. 9.8%
Peptide Content (N%) 80.0%min. 88.0%
Amino Acid Composition ±10% of theoretical Complies
Single Impurity (HPLC) 1.0%max. 0.45%
MS(ESI)
 
Consistent
 
Complies
Mass Balance
 
95.0~105.0%
 
98.0%

Its proposed mechanism of action is the desensitization of pituitary GnRH receptors leading to a decrease in gonadotropin release, and ovarian hormone serum concentrations similar to those achieved in postmenopausal women.  Nafarelin is administered by nasal inhalation and has been generally well tolerated.

It is associated with a high incidence of adverse effects but they are rarely severe enough to cause withdrawal from treatment, and those occurring most frequently--hot flashes, vaginal dryness, and decreased libido--are a consequence of the hypoestrogenemia induced by the drug. Increased bone turnover occurs in women on nafarelin but biochemical parameters return to pretreatment concentrations by six months after termination of treatment. This agent's place in the therapy of endometriosis will be determined as clinical experience accumulates.

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Contact us if you need more details on Nafarelin Acetate Dosage. We are ready to answer your questions on packaging, logistics, certification or any other aspects about Nafarelin Acetate Effects、Nafarelin Acetate Nasal Spray. If these products fail to match your need, please contact us and we would like to provide relevant information.

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