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Home > Products > Pharmaceutical And Medical > Others Pharmaceutical And Medical > USP 99.8% Pure Flumazenil Powder CAS 78755-81-4 Flumazepil Pharmaceutical

USP 99.8% Pure Flumazenil Powder CAS 78755-81-4 Flumazepil Pharmaceutical

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Basic Info

Model No.:  CAS 78755-81-4

Product Description

Model NO.: CAS 78755-81-4 Customized: Non-Customized Suitable for: Adult Purity: >99% Flumazenil Purity: 99.8% Characters: White Crystalline Powder MOQ: 10g Packing: 100g/Foil Bag or as Your Requirement Transport Package: 1kg/Bag, 25kg Origin: China Powder: Yes Certification: GMP, ISO 9001, Ep5 State: Solid Model No: 78755-81-4 Standard: USP3 Guarantees The Nature Time: 36 Months Transportation: DHL, UPS, TNT, EMS, FedEx or Other Trademark: Sendi Specification: 1kg/bag, 25KG HS Code: 3001200010 Product name:Flumazenil
Other name:Flumazepil
CAS No:78755-81-4
Molecular formula:C15H14FN3O3
Molecular weight:303.29
EINECS:N/A
Appearance: White crystalline powder
Catalogue:Pharmaceutical materials drug
Key words:Flumazenil ampul;Flumazenil plm;Flumazenil uses;Flumazenil brand name;Flumazenil half life;Flunarizine;flumacenilo;adenosine;fentanil;Flumazenil presentation;Flumazenil dosis;Flumazenil nombre comercial;naloxon;fluminense;Flumazenil dose;ondansetron;;Flumazenil injection;Flumazenil antidoto;Flumazenil vademecum;Flumazenil antidote;benzodiazepine

What is Flumazenil
Reversing drowsiness, sedation, and other effects caused by benzodiazepine
Flumazenil is a benzodiazepine antagonist. It works by blocking receptors in the brain and central nervous system that benzodiazepine need to reach to be active, which helps reduce drowsiness and sedation.

Flumazenil benefits and effects:
(1)Flumazenil is of benefit in patients who become excessively drowsy after benzodiazepine are used for either diagnostic or therapeutic procedures.
(2)It has been used as an antidote in the treatment of benzodiazepine overdoses. There are many complications that must be taken into consideration when used in the acute care setting.These include lowered seizure threshold, agitation, and anxiousness. Flumazenil's short half-life requires multiple doses and careful patient monitoring to prevent recurrence of overdose symptoms.
 
(4)Flumazenil has been effectively used to treat overdoses of non-benzodiazepine hypnotics, such as zolpidem, zaleplon and zopiclone.

Flumazenil CERTIFICATE OF ANALYSIS
Items of analysis Specification Results
Appearance White crystalline powder White Crystalline Powder  
Identification The sample'S IR spectrum is according with spectrum of  Flumazenil,The retention time of the major peak Flumazenil in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation Conforms
Melting point 198ºC to 202ºC 200.6ºC to 200.9ºC
Appearance of solution The solution is clear and is not Intenser than reference solution BY7   Conforms
Impurity C  NMT 0.2% 0.02%
Impurity A NMT 0.10% Not detected
Impurity B NMT 0.2% 0.03%
Impurity D NMT 0.10% 0.03%
Impurity E NMT 0.10% Not detected
Impurity F NMT 0.10% Not detected
Individual unknown impurituy NMT 0.10% 0.02%
Total impurities NMT 0.5% 0.1%
Loss on drying NMT 0.5% 0.2%
Sulphated ash NMT 0.1% 0.05%
Heavy metals ≤0.5 ppm 5ppm
Microbial limits( for Injection) Bacteria not more than 50CFU/g <10 CFU/g
Microbial limits Mildew and microzyme not more than 50CFU/g <10 CFU/g
Microbial limits Escherichia coli absence Absence
Ethanol NMT2000ppm Not detected
Chloroform   NMT30ppm Not detected
Acetic acid    NMT4000ppm Not detected
Dichloromethane NMT600ppm <0.002%
Ethyl ethanoate NMT5000ppm <0.003%
DMF NMT750ppm Not detected
Assay (On dried substance) 98.0-102.0% 99.80%
Bacterial endotoxins not more than 25.0 USP Endotoxin Units per mg of flumazenil. not more than 8.0 USP Endotoxin Units per mg of flumazenil.
Guarantees the nature time 36 months 36 months

Other Pharmaceutical Raw Material
NO.1 Noopept CAS:157115-85-0
NO.2 Piracetam CAS:7491-74-9
NO.3 Idebenone CAS:58186-27-9
NO.4 phenylpiracetam CAS:77472-70-9
NO.5 Pramiracetam CAS:68497-62-1
NO.6 Rivastigmine CAS:123441-03-2
NO.7 Coluracetam CAS:135463-81-9
NO.8 Entacapone CAS:130929-57-6
NO.9 Oxiracetam CAS:62613-82-5
NO.10 Aniracetam CAS:72432-10-1
NO.11 Donepezil CAS:120014-06-4
NO.12 brivaracetam CAS:357336-20-0
NO.13 Etiracetam CAS:33996-58-6
NO.14 Raubasine CAS:483-04-5
NO.15 Rivastigmine tartrate CAS:129101-54-8
NO.16 Sunifiram CAS:314728-85-3

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